DNAH9

Dynein heavy chain 9, axonemal is a protein that in humans is encoded by the DNAH9 gene.^[5][6][7]

AliasesDNAH9, DNAH17L, DNEL1, DYH9, Dnahc9, HL-20, HL20, dynein axonemal heavy chain 9, CILD40

External IDsOMIM: 603330; MGI: 1289279; HomoloGene: 20357; GeneCards: DNAH9; OMA:DNAH9 - orthologs

Chr.Chromosome 17 (human)^[1]

End11,969,748 bp^[1]

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DNAH9
Identifiers
Aliases	DNAH9, DNAH17L, DNEL1, DYH9, Dnahc9, HL-20, HL20, dynein axonemal heavy chain 9, CILD40
External IDs	OMIM: 603330; MGI: 1289279; HomoloGene: 20357; GeneCards: DNAH9; OMA:DNAH9 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p12 Start 11,598,470 bp[1] End 11,969,748 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B3|11 40.53 cM Start 65,722,108 bp[2] End 66,059,377 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube bronchial epithelial cell olfactory zone of nasal mucosa mucosa of paranasal sinus epithelium of nasopharynx C1 segment sperm testicle caudate nucleus secondary oocyte Top expressed in choroidal fissure zygote secondary oocyte choroid plexus of fourth ventricle olfactory epithelium primary oocyte Epithelium of choroid plexus embryo neural layer of retina dentate gyrus of hippocampal formation granule cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function microtubule motor activity nucleotide binding ATPase activity ATP binding cytoskeletal motor activity minus-end-directed microtubule motor activity dynein light chain binding dynein intermediate chain binding dynein light intermediate chain binding Cellular component cytoplasm axoneme cell projection cilium microtubule cytoskeleton dynein complex motile cilium 9+2 motile cilium distal portion of axoneme Biological process microtubule-based movement cell projection organization cilium movement Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1770 237806 Ensembl ENSG00000007174 ENSMUSG00000056752 UniProt Q9NYC9 n/a RefSeq (mRNA) NM_001372 NM_004662 NM_001099633 RefSeq (protein) NP_001363 NP_004653 n/a Location (UCSC) Chr 17: 11.6 – 11.97 Mb Chr 11: 65.72 – 66.06 Mb PubMed search [3] [4]
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This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined.^[7]