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DOI-NDEPA

Pharmaceutical compound From Wikipedia, the free encyclopedia

DOI-NDEPA is a chemical compound of the phenethylamine, DOx, and NDEPA families.[1] It is the N-(N,N-diethylpropylamide) (NDEPA) derivative of the psychedelic drug DOI.[1] The drug can also be thought of as a derivative of DOI with an LSD-like N,N-diethylamide moiety.[1] A quantitative structure–activity relationship (QSAR) predicted that DOI-NDEPA would bind with high affinity to the serotonin 5-HT2A receptor.[1] Its predicted affinity (Ki) was 3.2 nM.[1] DOI-NDEPA was first described in the scientific literature by 1999.[1]

Other namesNDEPA-DOI; "Compound ko3"[1]
ATC code
  • None
Quick facts Clinical data, Other names ...
DOI-NDEPA
Clinical data
Other namesNDEPA-DOI; "Compound ko3"[1]
Drug classPossible serotonin 5-HT2A receptor modulator[1]
ATC code
  • None
Identifiers
CAS Number
Chemical and physical data
FormulaC18H29IN2O3
Molar mass448.345 g·mol−1
3D model (JSmol)
  • IC1C=C(C(=CC=1OC)CC(C)N(CCC(=O)N(CC)CC)[H])OC
  • InChI=1S/C18H29IN2O3/c1-6-21(7-2)18(22)8-9-20-13(3)10-14-11-17(24-5)15(19)12-16(14)23-4/h11-13,20H,6-10H2,1-5H3
  • Key:AFLFXZWRYYBMHK-UHFFFAOYSA-N
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