DPYSL3

DPYSL3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4BKN, 4CNS, 4CNT, 4CNU
Identifiers
Aliases	DPYSL3, CRMP-4, CRMP4, DRP-3, DRP3, LCRMP, ULIP, ULIP-1, dihydropyrimidinase like 3
External IDs	OMIM: 601168; MGI: 1349762; HomoloGene: 20361; GeneCards: DPYSL3; OMA:DPYSL3 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	147,510,068 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	43,571,351 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; saphenous vein; ; gastric mucosa; ; tail of epididymis; ; right coronary artery; ; tibial arteries; ; ascending aorta; ; urethra; ; optic nerve;
	Top expressed in
	superior cervical ganglion; ; Rostral migratory stream; ; barrel cortex; ; ganglionic eminence; ; seminiferous tubule; ; optic nerve; ; medial ganglionic eminence; ; neural tube; ; sexually immature organism; ; pineal gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding; protein binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; chondroitin sulfate binding; hydrolase activity; filamin binding;
Cellular component	cytoplasm; cell body; filamentous actin; cytosol; cell projection; exocytic vesicle; growth cone; lamellipodium; extracellular space; synapse;
Biological process	negative regulation of neuron projection development; regulation of cell migration; regulation of neuron projection development; neuron development; actin filament bundle assembly; negative regulation of cell migration; response to axon injury; actin crosslink formation; positive regulation of neuron projection development; protein homooligomerization; positive regulation of filopodium assembly; cellular response to cytokine stimulus;
	Sources:Amigo / QuickGO
Orthologs
	1809
	22240
	ENSG00000113657
	ENSMUSG00000024501
	Q14195
	Q62188
	NM_001197294; NM_001387
	NM_001136086; NM_001291455; NM_009468
	NP_001184223; NP_001378
	NP_001129558; NP_001278384; NP_033494
	Wikidata
View/Edit Human	View/Edit Mouse

Dihydropyrimidinase-related protein 3 is an enzyme that in humans is encoded by the DPYSL3 gene.^[5]^[6]^[7] A recent bioinformatics study suggested that the DPYSL3 gene might have a prognostic role in neuroblastoma.^[8]