Dacemazine

Dacemazine (INN, also known as Ahistan and Histantine)^[1] is a phenothiazine derivative which acts as a histamine antagonist at the H₁ subtype. First described in 1951, it was never marketed as a drug on its own, although a combination of dacemazine and di-tert-butylnaphthalenesulfonate was sold as an antispasmodic and antitussive under the trade name Codopectyl.^[1] It was also assessed as a possible anticancer drug.^[2]

ATC code

• none

CAS Number

• 518-61-6 ^N

PubChem CID

• 68846

ChemSpider

• 62079 ^Y

Quick facts Clinical data, ATC code ...

Dacemazine

Clinical data
ATC code	none
Identifiers
IUPAC name 2-dimethylamino-1-phenothiazin-10-ylethanone
CAS Number	518-61-6 N
PubChem CID	68846
ChemSpider	62079 Y
UNII	88D34UY0QI
ChEMBL	ChEMBL2107547 N
CompTox Dashboard (EPA)	DTXSID70199733
Chemical and physical data
Formula	C16H16N2OS
Molar mass	284.38 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(N1c3c(Sc2c1cccc2)cccc3)CN(C)C
InChI InChI=1S/C16H16N2OS/c1-17(2)11-16(19)18-12-7-3-5-9-14(12)20-15-10-6-4-8-13(15)18/h3-10H,11H2,1-2H3 Y Key:HKUCYAHWPVLPFN-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

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