Dachshund (gene)
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| Dachshund | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | dac | ||||||
| UniProt | Q24030 | ||||||
| |||||||
dachshund (dac) is a gene involved in the development of the arthropod compound eye[1] which also plays a role in leg development.[2] It is activated by the Distal-less (Dll) gene.[3]
Dachshund homologue (DACH1) regulates tumorigenesis in humans as a part of the Retinal Determination Gene Network (RDGN) complex, with cancer patients showing altered DACH1 expression.[4] Its homologs form the SKI/SNO/DAC family (Pfam PF02437).
