Daf-5
From Wikipedia, the free encyclopedia
| Dauer Formation abnormality gene 5 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | Daf-5 | ||||||
| Entrez | 175054 | ||||||
| RefSeq (mRNA) | NM_064540.5 | ||||||
| RefSeq (Prot) | NP_496941.1 | ||||||
| UniProt | G5EDM7 | ||||||
| Other data | |||||||
| Chromosome | II: 14.03 - 14.04 Mb | ||||||
| |||||||
Daf-5 is an ortholog of the mammalian protein Sno/Ski，which present in the nematode worm Caenorhabditis elegans on the downstream of TGFβ signaling pathway.[1] Without daf-7 signal, daf-5 combined with daf-3, co-SMAD for C. elegans, to form a heterodimer and started dauer development.[2]
