Delftia tsuruhatensis

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Delftia tsuruhatensis
Scientific classification Edit this classification
Domain: Bacteria
Kingdom: Pseudomonadati
Phylum: Pseudomonadota
Class: Betaproteobacteria
Order: Burkholderiales
Family: Comamonadaceae
Genus: Delftia
Species:
D. tsuruhatensis
Binomial name
Delftia tsuruhatensis
Shigematsu et al. 2003, sp. nov.[1]
Type strain
ATCC BAA-554, DSM 17581, IFO 16741, NBRC 16741, T7[2]

Delftia tsuruhatensis is a Gram-negative, rod-shaped, catalase- and oxidase-positive, motile bacterium from the Comamonadaceae family. It was first isolated from a wastewater treatment plant in Japan in 2003.[3] D. tsuruhatensis is an opportunistic and emergent pathogen.[4] All documented human infections are healthcare-associated.[4][5][6][7]

Biofilm interactions

Cells are slightly curved, short rod-shaped cells that occur singly or in pairs. Cells are 0.7–1.2 μm wide and 2.4–4.0 μm long.[3]

D. tsuruhatensis can degrade phenolic compounds[8] and aniline,[9] which are often pollutants of soil and water.

D. tsuruhatensis can inhibit quorum sensing and biofilm formation, which could inform new therapeutic drugs against antibiotic-resistant bacteria.[10] D. tsuruhatensis inhibits quorum sensing and suppresses biofilm formation against Pseudomonas aeruginosa and other pathogens.[10][11] These activities increase P. aeruginosa's susceptibility to antibiotics by 2 to 3 times.[12]

Applications

In 2023, researchers published evidence in Science that D. tsuruhatensis prevents the development of malaria in mosquitos by secreting harmane. Mosquitos infected by the bacteria had 75% fewer Plasmodium oocysts and featured infection rates one third those of uninfected mosquitoes.[13][14][15][16]

See also

References

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