Denifanstat

Denifanstat
Clinical data
Other names	TVB-2640
Legal status
Legal status	Investigational;
Identifiers
	IUPAC name 4-[1-[4-Cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl]benzonitrile;
CAS Number	1399177-37-7;
PubChem CID	66548316;
ChemSpider	58955989;
UNII	4GF95B2LZA;
ChEMBL	ChEMBL3661754;
Chemical and physical data
Formula	C27H29N5O
Molar mass	439.563 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC(=C(C=C1C(=O)N2CCC(CC2)C3=CC=C(C=C3)C#N)C4=NNC(=N4)C)C5CCC5;
	InChI InChI=1S/C27H29N5O/c1-17-14-24(22-4-3-5-22)25(26-29-18(2)30-31-26)15-23(17)27(33)32-12-10-21(11-13-32)20-8-6-19(16-28)7-9-20/h6-9,14-15,21-22H,3-5,10-13H2,1-2H3,(H,29,30,31); Key:BBGOSBDSLYHMRA-UHFFFAOYSA-N;

Other namesTVB-2640

Denifanstat (TVB-2640) is a small-molecule drug and fatty acid synthase inhibitor. Developed by Sagimet Biosciences, it has been tested in various types of cancer^[1]^[2]^[3]^[4] and for non-alcoholic steatohepatitis.^[5]

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