Born on February 8, 1950, to Andre and Vera Maillet in New York City, Main grew up in Venezuela and Puerto Rico, returning to the United States only for college.
Starting with a trip to Honduras in 1995 as with St. Stephen's Episcopal Church, Belvedere, CA, Main saw the urgent need for anti-retroviral medication. Main is the president of Siempre Unidos California.
In 2007, the Yale College of Divinity recognized her important work with an honorary doctor of humane letters.[1]
Maternal fetal medicine
Main has served on the board of the Society of Maternal Fetal Medicine and was a founding fellow of the American College of Medical Genetics. In 1990, she established California Pacific's Prenatal Diagnosis Center, which has grown into one of the most respected Prenatal Diagnosis centers in the United States. Main regularly appears on lists of the best doctors in maternal-fetal medicine.[citation needed]