Dexoxadrol

Chemical compound From Wikipedia, the free encyclopedia

Dexoxadrol (Dioxadrol) is a dissociative anaesthetic drug which has been found to be an NMDA antagonist and produces similar effects to PCP in animals. Dexoxadrol, along with another related drug etoxadrol, were developed as analgesics for use in humans, but development was discontinued after patients reported side effects such as nightmares and hallucinations.[1][2]

ATC code
  • none
Legal status
  • In general: legal
Quick facts Clinical data, ATC code ...
Dexoxadrol
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: legal
Identifiers
  • (2S)-2-[(4S)-2,2-Di(phenyl)-1,3-dioxolan-4-yl]piperidine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H23NO2
Molar mass309.409 g·mol−1
3D model (JSmol)
  • O1C[C@@H](OC1(c2ccccc2)c3ccccc3)[C@H]4NCCCC4
  • InChI=1S/C20H23NO2/c1-3-9-16(10-4-1)20(17-11-5-2-6-12-17)22-15-19(23-20)18-13-7-8-14-21-18/h1-6,9-12,18-19,21H,7-8,13-15H2/t18-,19+/m0/s1 checkY
  • Key:HGKAMARNFGKMLC-RBUKOAKNSA-N checkY
 ☒NcheckY (what is this?)  (verify)
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See also

  • WMS-2539, a fluorinated derivative of dexoxadrol

References

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