DicF RNA
From Wikipedia, the free encyclopedia
| DicF RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of DicF | |
| Identifiers | |
| Symbol | DicF |
| Rfam | RF00039 |
| Other data | |
| RNA type | Gene; antisense |
| Domain | Bacteria |
| GO | GO:0003729 |
| SO | SO:0000644 |
| PDB structures | PDBe |
DicF RNA is a non-coding RNA that is an antisense inhibitor of cell division gene ftsZ.[1] DicF is bound by the Hfq protein which enhances its interaction with its targets. Pathogenic E. coli strains possess multiple copies of sRNA DicF in their genomes, while non-pathogenic strains do not. DicF and Hfq are both necessary to reduce FtsZ protein levels, leading to cell filamentation under anaerobic conditions.[2]
