Dihydroorotase

Class of enzymes From Wikipedia, the free encyclopedia

Dihydroorotase (EC 3.5.2.3, carbamoylaspartic dehydrase, dihydroorotate hydrolase) is an enzyme which converts carbamoyl aspartic acid into 4,5-dihydroorotic acid in the biosynthesis of pyrimidines.[1][2] It forms a multifunctional enzyme with carbamoyl phosphate synthetase and aspartate transcarbamoylase. Dihydroorotase is a zinc metalloenzyme.[3]

Quick facts carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, Identifiers ...
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Dihydroorotase (fragment) dimer, Human
Identifiers
SymbolCAD
NCBI gene790
HGNC1424
OMIM114010
RefSeqNM_004341
UniProtP27708
Other data
EC number3.5.2.3
LocusChr. 2 p22-p21
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StructuresSwiss-model
DomainsInterPro
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