Dihydroorotate dehydrogenase (fumarate)

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Dihydroorotate dehydrogenase (fumarate) (EC 1.3.98.1, dihydroorotate oxidase, pyr4 (gene)) is an enzyme with systematic name (S)-dihydroorotate:fumarate oxidoreductase.[1][2]

The enzyme is found in the bacterium Lactococcus lactis and the yeast Saccharomyces cerevisiae.[3][4][5][6] It contains the cofactor, flavin mononucleotide and catalyses the following chemical reaction which is part of the biosynthesis of pyrimidine nucleotides.[7]

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