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Diphenylmethylpiperazine

Chemical compound From Wikipedia, the free encyclopedia

Diphenylmethylpiperazine, also known as benzhydrylpiperazine, is a chemical compound and piperazine derivative. It features a piperazine ring with a benzhydryl (diphenylmethyl) group bound to one of the nitrogens.[1][2] Cyclizine, an antihistamine and anticholinergic drug used to treat motion sickness, is the methylated derivative of diphenylmethylpiperazine, and the antihistamine cinnarizine is another derivative. 1-Benzhydrylpiperazine has been described as having "amphetamine-like effects".[3]

Quick facts Names, Identifiers ...
Diphenylmethylpiperazine
Skeletal formula of diphenylmethylpiperazine
Ball-and-stick model of the diphenylmethylpiperazine molecule
Names
Preferred IUPAC name
1-(Diphenylmethyl)piperazine
Other names
1-benzhydrylpiperazine; Norcyclizine
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.011.516 Edit this at Wikidata
UNII
  • InChI=1S/C17H20N2/c1-3-7-15(8-4-1)17(16-9-5-2-6-10-16)19-13-11-18-12-14-19/h1-10,17-18H,11-14H2
  • c1c(cccc1)C(c2ccccc2)N3CCNCC3
Properties
C17H20N2
Molar mass 252.361 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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