Dolosigranulum pigrum
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| Dolosigranulum pigrum | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Bacillati |
| Phylum: | Bacillota |
| Class: | Bacilli |
| Order: | Lactobacillales |
| Family: | Carnobacteriaceae |
| Genus: | Dolosigranulum |
| Species: | D. pigrum |
| Binomial name | |
| Dolosigranulum pigrum Aguirre et al. 1994[1] | |
| Type strain | |
| ATCC 51524, CCUG 33392, CIP 104051, IFO 15550, LMG 15126, NBRC 15550, NCFB 2975, NCIMB 702975, R91/1468[2] | |
Dolosigranulum pigrum is a Gram-positive bacterium from the genus of Dolosigranulum.[1][2][3] Dolosigranulum pigrum can cause infections in the upper respiratory tract, as well as nosocomial pneumonia and sepsis.[4][5][6] The metabolism of this organism has been reconstructed. It is available as a genome-scale metabolic model, which indicates incomplete biochemical pathways within the central carbon metabolism.[7] Consequently, its metabolism depends on other members of its microbial habitat, such as Staphylococcus aureus, whose growth D. pigrum negatively impacts.[8]
D. pigrum is highly adapted to the human nasal passages. In an analysis of 8,184 samples from six human body sites, Dolosigranulum sequencing reads were identified in 41% of nasal samples, 15% of skin samples, and less than 1% of fecal and oral cavity samples. Moreover, in samples in which Dolosigranulum was detected, the organism was far more abundant in nasal samples (18% mean relative abundance) than in samples from other body sites (less than 2% mean relative abundance). Analyses of data from the Earth Microbiome Project revealed that Dolosigranulum reads were rarely identified in environmental sources (e.g., water, soil) but were found in samples from a variety of animal species, including rodents, fish, birds, dogs, and primates.[9]
