Wyatt first worked as a secretary, meeting her husband Donald Wyatt while working for American Overseas Airlines in Gander.[3] She later returned to Memorial University of Newfoundland to study nursing.[3]
Wyatt first won election to St. John's City Council in 1969 as the city's first female councilor.[2] She ran for the mayoralty in 1973, winning the election and serving two terms in office.[2] Her term as mayor was marked by accomplishments including the city's hosting of the Canada Summer Games in 1977,[3] a shift from rental-value to capital-value municipal tax assessment,[2] the adoption of a ward system for city council elections,[2] and the construction of many of the city's modern office buildings.[2]
Wyatt was defeated by John Joseph Murphy in the 1981 election.[2] She was later reelected as a councillor at large in 1985, and remained a sitting member of city council until her death;[4] she died just two days before the city's 2001 municipal election, and was posthumously reelected to her seat on September 25.[4] A by-election was held on November 27 of that year, and was won by Sandy Hickman.[4]
She was a candidate for provincial office twice, running as an independent candidate in St. John's Centre[3] and later for the leadership of the Progressive Conservative Party of Newfoundland and Labrador in the party's 1979 leadership convention.[3] In the PC race, she garnered no votes. She didn't vote for herself, admitting that she had run more "to shake things up" than out of a serious desire to actually lead the party,[3] and was eliminated on the first ballot.[3]