Wikiwand AI

Reticular pigmented anomaly of the flexures

Medical condition From Wikipedia, the free encyclopedia

Reticular pigmented anomaly of the flexures (also known as dark dot disease and Dowling–Degos disease) is a fibrous anomaly of the flexures or bending parts of the axillae, neck and inframammary/sternal areas.[2]:856 It is an autosomal-dominant pigmentary disorder that may appear in adolescence or adulthood. This condition is due to mutations in structural/desmosomal proteins found within stratified squamous epithelium.[3]

Other namesKitamura reticulate acropigmentation[1]
SpecialtyDermatology
Quick facts Other names, Specialty ...
Reticular pigmented anomaly of the flexures
Other namesKitamura reticulate acropigmentation[1]
SpecialtyDermatology
Close

Dark dot disease is associated with KRT5.[4]

See also

References

Related Articles

Timelines

Top Qs

Fact Checks