Reticular pigmented anomaly of the flexures

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Reticular pigmented anomaly of the flexures (also known as dark dot disease and Dowling–Degos disease) is a fibrous anomaly of the flexures or bending parts of the axillae, neck and inframammary/sternal areas.[2]:856 It is an autosomal-dominant pigmentary disorder that may appear in adolescence or adulthood. This condition is due to mutations in structural/desmosomal proteins found within stratified squamous epithelium.[3]

Other namesKitamura reticulate acropigmentation[1]
SpecialtyDermatology
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Reticular pigmented anomaly of the flexures
Other namesKitamura reticulate acropigmentation[1]
SpecialtyDermatology
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Dark dot disease is associated with KRT5.[4]

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References

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