Draft:BioSpring
Contract manufacturer of therapeutic oligonucleotides
From Wikipedia, the free encyclopedia
BioSpring is a Contract Manufacturing and Development Organization (CDMO) for Biotech and Pharma companies, specialized in oligonucleotides, and located in Frankfurt a.M. Germany.
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 | |
| Company type | Private |
|---|---|
| Industry | Pharmaceutical Manufacturing |
| Founded | 1997 |
| Headquarters | Frankfurt a.M, Germany |
| Website | www.biospring.net |
History
BioSpring was founded in 1997, by Hüseyin Aygün and Sylvia Wojczewski, then graduate students at Goethe-University-Frankfurt. BioSpring's headquarters are located in Frankfurt-Fechenheim and the company is still privately held and independent. Another production site is currently being built in neighboring Offenbach a.M.[1][2]
The company employs about 600 people with 40 nationalities (as of March 2026). The average employee age is 33 years and half of employees and managers are female.
Products
The active pharmaceutical ingredients, which BioSpring manufactures, serve diverse innovative treatments for formerly untreatable diseases, among others, cardiovascular diseases, metabolic diseases and neuromuscular diseases, and cancer.[3][4][5] The company is specialized in the production and analysis of nucleic acids and specifically oligonucleotides. These molecules, which are short synthetic equivalents of natural genes, are being used in research and development, diagnostics and for therapeutic purposes. BioSpring also manufactures guide RNA for modern gene editing therapies, e.g. CRISPR/Cas9-based treatments. Nuleic acids and oligonucleotides produced by BioSpring:
- Antisense Oligonucleotides (ASO)
- Small interfering RNA (siRNA)
- Guide RNA for genome editing purposes (e.g., CRISPR/Cas9)
- Aptamers
- mRNA