Draft:David Nelson Ku
American bioengineer and physician
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David Nelson Ku is an American bioengineer and physician who is a Regents’ Professor of Mechanical Engineering and Lawrence P. Huang Chair Professor for Engineering Entrepreneurship at the Georgia Institute of Technology.[1] He also holds an appointment as Professor of Surgery at Emory University.[1] His work integrates fluid mechanics, vascular biology, and clinical medicine, and is known for research on wall shear stress in atherosclerosis and the biophysics of arterial thrombosis.
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Georgia Institute of Technology (MS, PhD)
Emory University (MD)
Emory University
David Nelson Ku | |
|---|---|
| Education | Harvard University (BA) Georgia Institute of Technology (MS, PhD) Emory University (MD) |
| Known for | Hemodynamic mechanisms of atherosclerosis; shear-induced platelet aggregation; biomedical device development |
| Scientific career | |
| Fields | Bioengineering, Hemodynamics, Thrombosis, Biomedical devices |
| Institutions | Georgia Institute of Technology Emory University |
Education and training
Academic career
Research
Hemodynamics and atherosclerosis
Ku’s early research examined quantitative associations between disturbed wall shear stress and localization of atherosclerosis. A 1985 study reported agreement between regions of low and oscillatory shear stress and intimal thickening in the human carotid bifurcation.[2]
An invited review, Blood Flow in Arteries, published in the Annual Review of Fluid Mechanics (1997), summarized engineering and physiological perspectives on arterial flow.[3]
Arterial thrombosis and shear-induced platelet aggregation
Ku’s later research examined mechanisms of arterial thrombosis under high shear conditions, including experimental stenosis models and analysis of shear-dependent platelet aggregation.[4]
Biomedical devices and commercialization
Ku has contributed to translational research in biomedical devices, including work on poly(vinyl alcohol) (PVA) hydrogel biomaterials investigated for soft tissue and cartilage applications.[5]
Related hydrogel formulations have been described in patents associated with SaluMedica, LLC, a biomedical company focused on hydrogel-based implant technologies.[6]
Honors and awards
Ku received the Gustus L. Larson Memorial Award of the American Society of Mechanical Engineers (1996).[7]
He received the Y. C. Fung Young Investigator Award from the ASME Bioengineering Division (1989).[8]
He was elected a Fellow of the American Institute for Medical and Biological Engineering (AIMBE) (1998).[9]
Additional honors listed on his Georgia Tech faculty biography include the NSF Presidential Young Investigator Award (1987) and the American Heart Association Young Investigator Award (1989).[1]
Selected publications
- Ku DN et al. Pulsatile flow and atherosclerosis in the human carotid bifurcation. Arteriosclerosis. 1985.
- Ku DN. Blood flow in arteries. Annual Review of Fluid Mechanics. 1997.
- Kim DJ, Ku DN. Occlusive thrombosis in arteries. APL Bioengineering. 2019.