Draft:Global Health EDCTP3
European Union institutionalised partnership
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Global Health EDCTP3 (officially, Global Health European & Developing Countries Clinical Trials Partnership 3 Joint Undertaking) is a European Union institutionalised partnership supporting collaborative research to address infectious diseases in sub-Saharan Africa. It focuses on accelerating the development of medical interventions such as vaccines, therapeutics, diagnostics and clinical strategies, while strengthening clinical research capacity and health research systems in Africa.[1][2] It builds on the legacy of the earlier European and Developing Countries Clinical Trials Partnership programmes, and is the third iteration.[3][4]
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Comment: In accordance with the Wikimedia Foundation's Terms of Use, I disclose that I have been paid by my employer for my contributions to this article. Albert Sanchez Carmona (talk) 14:38, 4 March 2026 (UTC)
- Michael Makanga, Executive Director
| Agency overview | |
|---|---|
| Formed | 2021 |
| Jurisdiction | European Union |
| Headquarters | Brussels, Belgium |
| Agency executive |
|
| Website | https://www.global-health-edctp3.europa.eu/ |
The partnership operates under the EU's research and innovation framework programme Horizon Europe and is implemented as a joint undertaking between the European Union and participating countries, represented by the EDCTP Association, and created by the Council Regulation (EU) 2021/2085, under Article 187 of the Treaty on the Functioning of the EU.[5]
The initiative aims to foster equitable research partnerships between Europe and Africa, supporting collaborative clinical trials and capacity-building activities that contribute to improved global health outcomes.
History
The Global Health EDCTP3 programme was launched in 2021 as the successor to the EDCTP programmes, which ran from 2003 to 2024.
The creation of Global Health EDCTP3 reflected a growing recognition of the need for stronger international cooperation in health research, particularly following lessons learned from global health crises such as the COVID-19 pandemic and recurring outbreaks of infectious diseases.[6]
The programme expanded the scope of earlier initiatives by:
- strengthening clinical research preparedness and response capacity
- increasing support for clinical trials and implementation research
- broadening engagement with African public health institutions
- reinforcing collaboration with international partners and philanthropic organisations
Objectives
Global Health EDCTP3 supports research and innovation aimed at reducing the burden of infectious diseases affecting sub-Saharan Africa, with a focus on translating scientific discoveries into accessible health interventions.
Its core objectives are:
- Reducing the socio-economic burden of infectious diseases in sub-Saharan Africa by promoting the development and uptake of new or improved health technologies.
- Increasing health security in sub-Saharan Africa and globally by strengthening research capacities for preparedness and response to control infectious diseases.
These general objectives are supported by the following specific objectives:
- Clinical research. Advance the development and use of new or improved medical interventions by funding clinical trials in sub-Saharan Africa.
- Capacity development. Build sustainable clinical research capacity and strengthen national health research systems in sub-Saharan Africa, ensuring adherence to the highest ethical and regulatory standards.
- Enhanced coordination. Facilitate better alignment of national efforts around a shared global health Strategic Research and Innovation Agenda.
- Epidemic preparedness. Strengthen the ability of sub-Saharan African countries to respond rapidly and effectively to infectious disease outbreaks through strengthened research capabilities.
- International cooperation. Foster collaboration across Africa, Europe, and beyond - including north–south, South-South, and North-North partnerships - and develop strategic alliances with the public and private sectors.
Activities
The programme funds projects through the EU's Horizon Europe research and innovation framework. These projects are selected through open calls for proposals and bring together partners across sectors and continents. The projects support a range of activities across the research and innovation cycle, including:
- Clinical trials for vaccines, therapeutics and diagnostics.
- Implementation research to improve access to health interventions.
- Capacity strengthening for clinical research sites, laboratories and regulatory bodies.
- Training and fellowships for researchers in Africa and Europe.
- Collaborative networks and platforms supporting disease surveillance and research preparedness.
Projects funded by the programme typically involve multinational research consortia combining universities, research institutes, hospitals, public health agencies and industry partners from Europea and sub-Saharan Africa.
Research priorities per disease area
Global Health EDCTP3 activities focus on this list of disease areas:
- HIV/AIDS
- Tuberculosis (TB)
- Malaria
- Neglected infectious diseases (NTDs)
- Diarrhoeal diseases
- Lower respiratory tract infections
- Emerging and re-emerging infectious diseases
- Climate crisis-related infectious diseases
- Antimicrobial resistance (AMR)
- Interaction of infectious diseases with non-communicable diseases