Draft:Liang Gao

American bioengineering resarcher From Wikipedia, the free encyclopedia

Liang Gao is an American-based researcher and academic. He is an Associate Professor of Bioengineering at the University of California, Los Angeles (UCLA), where he directs the Intelligent Optics Laboratory. Gao is known for his work in ultrafast optical imaging, multidimensional optical imaging, biophotonics, and computational optical imaging. His research has led to the development of advanced technologies such as Compressed Ultrafast Photography (CUP), Light-field tomography (LIFT), and Squeezed Light Field Microscopy (SLIM).

Education

Gao received his Bachelor of Science in Physics in 2005 and his Master of Science in Physics in 2007, both from Tsinghua University. He subsequently earned his Ph.D. in Applied Physics and Bioengineering from Rice University in 2011.[1]

Career and Research

Prior to joining the faculty at UCLA in 2020, Gao was an Assistant Professor in the Department of Electrical and Computer Engineering at the University of Illinois Urbana-Champaign (UIUC), where he was also affiliated with the Beckman Institute for Advanced Science and Technology.[2]

At UCLA, Gao's Intelligent Optics Laboratory focuses on developing next-generation multidimensional optical bioimaging devices. His work leverages advances in computational optics and AI, micro-fabrication, and detector technology to maximize the information content acquired from optical measurements. His lab actively conducts research in biomedical imaging and biophotonics.

Gao has made notable contributions to high-speed optics, creating tools that allow for transient imaging at multiple scales. His development of Compressed Ultrafast Photography (CUP) has been recognized as the world's fastest 2D camera. In addition, his invention of Light Field Tomography (LIFT) enabled the world's fastest 3D camera, capable of 4D capture (3D spatial and time) at ultra-fast frame rates, which holds broad applications for non-line-of-sight (NLOS) imaging.[3]

His recent work includes the development of Squeezed Light Field Microscopy (SLIM), an ultra-fast 3D visualization technique that can record over 1,000 3D frames per second to track individual blood cells and neural electric spikes in living tissue.[4] He also led the creation of Light-Field Tomographic Fluorescence Lifetime Imaging Microscopy (LIFT-FLIM), a method that transforms volumetric images to enable high-speed, high-resolution 3D fluorescence lifetime imaging with low-cost single-photon avalanche diode (SPAD) arrays.

Awards and Honors

Gao has received several significant awards for his contributions to optical science and bioengineering, including:

Selected Publications

  • Wang Z, et al. (2025). "Kilohertz volumetric imaging of in vivo dynamics using squeezed light field microscopy." Nat Methods.
  • Ma Y, et al. (2024). "Light-field tomographic fluorescence lifetime imaging microscopy." Proc Natl Acad Sci U S A.
  • Feng X, et al. (2022). "Compact light field photography towards versatile three-dimensional vision." Nat Commun.
  • Feng X, et al. (2021). "Ultrafast light field tomography for snapshot transient and non-line-of-sight imaging." Nat Commun.
  • Ma Y, et al. (2021). "High-speed compressed-sensing fluorescence lifetime imaging microscopy of live cells." Proc Natl Acad Sci U S A.
  • Park J, et al. (2020). "Snapshot multidimensional photography through active optical mapping." Nat Commun.
  • Gao L (2014). "Single-shot compressed ultrafast photography at one hundred billion frames per second." Nature.

References

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