Draft:Mübeccel Akdis
Immunologist
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Mübeccel Akdis
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Comment: In accordance with Wikipedia's Conflict of interest guideline, I disclose that I have a conflict of interest regarding the subject of this article. Ismalilogulur (talk) 10:01, 13 April 2026 (UTC)
Mübeccel Akdis[1] (born April 24, 1960, in Manisa, Turkey) is a Turkish-Swiss physician, immunologist, and professor at the [[University of Zurich]]. She is head of the Immune Regulation research[1] group at the [[Swiss Institute of Allergy and Asthma Research]] (SIAF[2]) in Davos, Switzerland. Her work has made significant contributions to the understanding of immune tolerance, regulatory T cells, regulatory B cells, and the mechanisms of allergen-specific immunotherapy.
Education
1985 Doctor of Medicine, Uludag University School of Medicine [3]
1995-1999 PhD study. Swiss Institute of Allergy and Asthma Research/Istanbul University Dept of Immunology. Immune pathogenesis of atopic dermatitis. [3][4]
Career
Akdis joined the Swiss Institute of Allergy and Asthma Research (SIAF) in 1995[5], initially working as a postdoctoral researcher. She was appointed group leader in 2003[4][3][4], establishing the Immune Dermatology (later Immune Regulation) research group. In 2005, she completed her habilitation (Venia Legendi)[2][3] in Experimental Immunology at the University of Zurich Medical Faculty, and was appointed Titular Professor[4][3] at the University of Zurich in 2005 (full professor designation confirmed by 2015–2016[3][4]). She has served as an editorial board member[6][7][8][3] of several scientific journals, including Allergy.
Research
Akdis's laboratory is known for its use of single-cell sequencing technologies to investigate the mechanisms of immune tolerance to allergens and to characterize regulatory and effector B cells. Her major research contributions [7][9][10]include:
- Mechanisms of allergen tolerance in human allergen-specific T and B cells
- Discovery of human B regulatory (Breg) cells — widely considered one of her most important scientific achievements
- Contributions to the discovery of human T regulatory (Treg) cells and human ILC regulatory cells (ILCreg)
- Allergen-specific immunotherapy, including the role of interleukin-10 (IL-10) and TGF-β in immune suppression
- High-dose allergen exposure models in humans
- Epithelial barrier function in allergy and asthma
- Immune responses to SARS-CoV-2 and COVID-19 immunopathology
She has published more than 400[11] peer-reviewed research articles and holds an h-index of approximately 100[9] (as of 2024–2025), with over 39,000[9][11] citations recorded on ResearchGate.