Dysidazirine

Natural chemical compound From Wikipedia, the free encyclopedia

Dysidazirine is an organic compound with formula C19H33NO2. It was discovered as a natural product in 1988 in the marine sponge Dysidea fragilis.[1] Chemically, it is a 2H-azirine derivative.

Quick facts Names, Identifiers ...
Dysidazirine
Names
IUPAC name
Methyl (2S)-3-[(E)-pentadec-1-enyl]-2H-azirine-2-carboxylate
Other names
(R)-Dysidazirine; (R)-(-)-dysidazirine
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C19H33NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(20-17)19(21)22-2/h15-16,18H,3-14H2,1-2H3/b16-15+/t18-/m0/s1
    Key: UOLCWKPNWDZCIP-ZPICJPFVSA-N
  • CCCCCCCCCCCCCC=CC(=N1)[C@H]1C(=O)OC
Properties
C19H33NO2
Molar mass 307.478 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 Â°C [77 Â°F], 100 kPa).
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Dysidazirine synthesis was reported for the first time in 1995.[2]

Dysidazirine kills the yeasts Candida albicans and Sacharamyces cerevisiae in vitro.[3] It also stops HCT-116 human colon cancer cells from growing.[1]

References

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