ERDRP-0519

ERDRP-0519
Legal status
Legal status	US: Investigational New Drug;
Identifiers
	IUPAC name 2-methyl-N-[4-[(2S)-2-(2-morpholin-4-ylethyl)piperidin-1-yl]sulfonylphenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide;
CAS Number	1374006-96-8 ;
PubChem CID	57521469;
ChemSpider	28514843;
UNII	V5S4Z5Q9VU;
Chemical and physical data
Formula	C23H30F3N5O4S
Molar mass	529.58 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cn1c(cc(n1)C(F)(F)F)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCC[C@H]3CCN4CCOCC4;
	InChI InChI=1S/C23H30F3N5O4S/c1-29-20(16-21(28-29)23(24,25)26)22(32)27-17-5-7-19(8-6-17)36(33,34)31-10-3-2-4-18(31)9-11-30-12-14-35-15-13-30/h5-8,16,18H,2-4,9-15H2,1H3,(H,27,32)/t18-/m0/s1; Key:JVZHTUQIMBYDSX-SFHVURJKSA-N;

ERDRP-0519 is an antiviral drug which is the first drug specifically developed to target the measles morbillivirus. It acts as an inhibitor of the viral enzyme RNA polymerase which is essential for viral replication, and in animal studies showed good oral bioavailability and protected ferrets from otherwise lethal doses of a morbillivirus when administered up to three days after infection.^[1]^[2]