ERP29
Protein-coding gene in humans
From Wikipedia, the free encyclopedia
Endoplasmic reticulum protein 29 (ERp29) is a chaperone protein that in humans is encoded by the ERP29 gene.[5]
External IDsOMIM: 602287; MGI: 1914647; HomoloGene: 4963; GeneCards: ERP29; OMA:ERP29 - orthologs
Function
ERp29 is a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide-isomerase family.[6] However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase.[6] The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.[5]
