Elephantiasis nostras
From Wikipedia, the free encyclopedia
| Elephantiasis nostras | |
|---|---|
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| Specialty | Dermatology |
Elephantiasis nostras, also known as "Holliman's Edema," is a disease that usually affects the lower legs or scrotum.[1] Swelling is accompanied by rough nodules or wart-like plaques on the skin. If the disease is not treated, it eventually results in pain and immobility.[2]
The disease can be described as a cutaneous condition, a final hypertrophic fibrosis following long standing chronic lymphangitis.[3]: 261
Although elephantiasis nostras resembles the elephantiasis caused by helminths, it is not a filarial disease. Instead, it is a complication of chronic lymphedema.[1] Both elephantiasis nostras and filarial elephantiasis are characterized by impaired lymphatic drainage, which results in excess fluid accumulation.[2]