Sinclair-Webb holds a degree from the University of Cambridge[2] and a PhD from the Department of Politics and Sociology at Birkbeck College with a thesis on religious and urban conflict.[3] She speaks Turkish.[4]
She taught cultural studies and humanities at Middlesex University[5] and also worked as an editor in the publishing industry in the areas of history, culture and politics of the Middle East.[2]
From 2003 to 2007, she worked as a researcher at Amnesty International specializing in Turkey, before joining Human Rights Watch in 2007 as a Senior Turkey Researcher in the Europe and Central Asia Department. Here she worked on issues such as police brutality, state-sponsored killings and enforced disappearances, as well as the misuse of terrorist laws.[2] She later became Turkey director of the human rights organization.
In 2016, Sinclair-Webb lived in Istanbul.[6]