He was part of the training group contingent at the Jaguares in the 2016 Super Rugby season, but despite this made 8 appearances for the Super Rugby side.
Pieretto joined English club Exeter Chiefs in November 2019 for the remainder of the 2019–20 season,[2] and joined Scottish Pro14 club Glasgow Warriors on a two-year contract from the 2020–21 season.[3]
He became Glasgow Warrior No. 313 on his debut on 28 August 2020 against Edinburgh at Murrayfield Stadium. He won the Most Improved Player award in the season 2020-21.
Having played rugby from a young age, Pieretto was selected for the Argentina under-19's team in 2013 to face neighbouring sides Uruguay U19, Chile U19 and Brazil U19. Enrique played in all 3 matches, scoring a try against Brazil on 21 September. In 2014, he was selected for the Pumitas for the 2014 IRB Junior World Championship in New Zealand.[7] He played in the 'big games' against Australia and England, but the team failed to win either game. He started in the Semifinals of the 9–12th place play-offs against Fiji, but did not make an appearance in the 9th place game against Scotland.[citation needed]
In January 2016, Pieretto was called up to the senior side for the 2016 Americas Rugby Championship, where he made an appearance in 4 of the uncapped games.[8] He made his international debut for the Pumas on 4 June 2016, starting against Chile in the 2016 Sudamérica Rugby Cup.[9] He was called up to the senior squad for their 2-test series against France and a test against Italy, coming off the bench against Italy and in the second test against France.[10] He was later called up for the 2016 Rugby Championship.[11]