Envonalkib

Envonalkib is a pharmaceutical drug for cancer treatment.^[1] It belongs to the class of anaplastic lymphoma kinase inhibitors (ALK inhibitors).^[2]

Trade names安洛晴

Legal status

• Rx in China

CAS Number

• 1621519-26-3

PubChem CID

• 76899983

Quick facts Clinical data, Trade names ...

Envonalkib

Clinical data
Trade names	安洛晴
Legal status
Legal status	Rx in China
Identifiers
IUPAC name 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[4-methoxy-6-[(2S)-2-methylpiperazin-1-yl]-3-pyridinyl]pyridin-2-amine
CAS Number	1621519-26-3
PubChem CID	76899983
ChemSpider	115010418
UNII	QB7KTQ7VW9
ChEMBL	ChEMBL5095063
Chemical and physical data
Formula	C24H26Cl2FN5O2
Molar mass	506.40 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@H]1CNCCN1C2=NC=C(C(=C2)OC)C3=CC(=C(N=C3)N)O[C@H](C)C4=C(C=CC(=C4Cl)F)Cl
InChI InChI=1S/C24H26Cl2FN5O2/c1-13-10-29-6-7-32(13)21-9-19(33-3)16(12-30-21)15-8-20(24(28)31-11-15)34-14(2)22-17(25)4-5-18(27)23(22)26/h4-5,8-9,11-14,29H,6-7,10H2,1-3H3,(H2,28,31)/t13-,14+/m0/s1 Key:BVGDAZBTIVRTGO-UONOGXRCSA-N

Close

In China, it is approved for the treatment of patients with ALK-positive locally advanced or metastatic non-small cell lung cancer (NSCLC) who have not received treatment with ALK inhibitors.^[3]