Estradiol butyrylacetate

Estradiol butyrylacetate
Clinical data
Trade names	Follikosid, Follikoside, Klimanosid
Other names	EBA; Estradiol 17β-butyrylacetate
Routes of; administration	Intramuscular injection
Drug class	Estrogen; Estrogen ester
Identifiers
	IUPAC name [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-oxohexanoate;
CAS Number	60883-80-9;
PubChem CID	91667672;
ChemSpider	52084153;
UNII	6ADI485E6C;
CompTox Dashboard (EPA)	DTXSID301046408 ;
Chemical and physical data
Formula	C24H32O4
Molar mass	384.516 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCC(=O)CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C;
	InChI InChI=1S/C24H32O4/c1-3-4-16(25)14-23(27)28-22-10-9-21-20-7-5-15-13-17(26)6-8-18(15)19(20)11-12-24(21,22)2/h6,8,13,19-22,26H,3-5,7,9-12,14H2,1-2H3/t19-,20-,21+,22+,24+/m1/s1; Key:LLWMXKOTHFASEO-NTYLBUJVSA-N;

Estradiol butyrylacetate (EBA), sold under the brand names Follikosid and Klimanosid-R Depot (with testosterone ketolaurate and reserpine), is an estrogen medication which is no longer marketed.^[1]^[2] It is an estrogen ester, specifically, an ester of estradiol.^[1] It is administered by intramuscular injection and a single 10 mg dose has been said to have a duration of action of 2 to 3 weeks.^[3]^[4] The excretion of EBA in women has been studied.^[5]^[6]