Estradiol cypionate/hydroxyprogesterone caproate

Estradiol cypionate/hydroxyprogesterone caproate (EC/OHPC), sold under the brand name Sinbios, is a combination medication of estradiol cypionate (EC), an estrogen, and hydroxyprogesterone caproate (OHPC), a progestin, which was reportedly used as a combined injectable contraceptive in women in the early 1970s.^[1] It contained 5 mg EC and 250 mg OHPC in oil solution, was provided in the form of 1 mL ampoules, and was administered by intramuscular injection at regular intervals.^[1] The medication was manufactured by the pharmaceutical company Mavi in Mexico.^[1]

Estradiol cypionateEstrogen

Hydroxyprogesterone caproateProgestogen

Trade namesSinbios

Other namesEC/OHPC

Quick facts Combination of, Hydroxyprogesterone caproate ...

Estradiol cypionate /
hydroxyprogesterone caproate

Estradiol cypionate (top) and hydroxyprogesterone caproate (bottom)
Combination of
Estradiol cypionate	Estrogen
Hydroxyprogesterone caproate	Progestogen
Clinical data
Trade names	Sinbios
Other names	EC/OHPC
Routes of administration	Intramuscular injection

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