Estradiol valerate/methenmadinone caproate

Estradiol valerate/methenmadinone caproate (EV/MMC), known by the tentative brand name Lutofollin, is a combination medication of estradiol valerate (EV), an estrogen, and methenmadinone caproate (MMC; superlutin caproate), a progestin, which was developed for potential use as a once-a-month combined injectable contraceptive but was never marketed.^[1][2][3] It contained 10 mg EV and 60 mg MMC in 1 mL oil solution and was intended for administration by intramuscular injection once every 4 weeks.^[1][2][3]

Estradiol valerateEstrogen

Methenmadinone caproateProgestogen

Other namesEV/MMC; Lutofollin

Routes of
administrationIntramuscular injection

Quick facts Combination of, Methenmadinone caproate ...

Estradiol valerate /
methenmadinone caproate

Estradiol valerate (top) and methenmadinone caproate (bottom)
Combination of
Estradiol valerate	Estrogen
Methenmadinone caproate	Progestogen
Clinical data
Other names	EV/MMC; Lutofollin
Routes of administration	Intramuscular injection
Identifiers
CAS Number	61829-06-9

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