Ethylene thiourea

Ethylene thiourea (ETU) is an organosulfur compound with the formula C₃H₆N₂S. It is an example of an N,N-disubstituted thiourea. It is a white solid. It is synthesized by treating ethylenediamine with carbon disulfide.^[3]

Quick facts Names, Identifiers ...

Ethylene thiourea

Names
Preferred IUPAC name Imidazolidine-2-thione
Other names 1,3-Ethylene-2-thiourea, N,N-Ethylenethiourea
Identifiers
CAS Number	96-45-7 Y
3D model (JSmol)	Interactive image
ChemSpider	2005851
ECHA InfoCard	100.002.280
PubChem CID	2723650
UNII	24FOJ4N18S Y
CompTox Dashboard (EPA)	DTXSID5020601
InChI InChI=1S/C3H6N2S/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6) Key: PDQAZBWRQCGBEV-UHFFFAOYSA-N InChI=1/C3H6N2S/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6) Key: PDQAZBWRQCGBEV-UHFFFAOYAQ
SMILES C1CNC(=S)N1
Properties
Chemical formula	C3H6N2S
Molar mass	102.16 g·mol−1
Appearance	White solid
Odor	Faint, amine-like
Melting point	203 Â°C (397 Â°F; 476 K)
Boiling point	347.18 Â°C (656.92 Â°F; 620.33 K)
Solubility in water	2% (30 °C)[1]
Vapor pressure	16 mmHg (20 °C)[1]
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	combustible[1]
Flash point	252.2 Â°C (486.0 Â°F; 525.3 K)
Lethal dose or concentration (LD, LC):
LD50 (median dose)	1832 mg/kg (oral, rat)[2]
NIOSH (US health exposure limits):
PEL (Permissible)	None[1]
REL (Recommended)	Ca Use encapsulated form.[1]
IDLH (Immediate danger)	Ca [N.D.][1]
Except where otherwise noted, data are given for materials in their standard state (at 25 Â°C [77 Â°F], 100 kPa). Infobox references

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Ethylene thioureas are an excellent accelerant of vulcanization of neoprene rubbers. In commercial use is the N,N'-diphenylethylenethiourea. Due to reproductive toxicity, carcinogenicity, and mutagenicity, alternatives are being sought to the ethylenethioureas. One candidate replacement is N-methyl-2-thiazolidinethione.^[4]

Ethylene thiourea can be used as a biomarker of exposure to ethylenebisdithiocarbamates (EBDTCs), which are frequently employed as fungicides in agriculture, mainly on fruits, vegetables and ornamental plants.^[5]