Ethylestradiol

Ethylestradiol, or 17α-ethylestradiol, also known as 17α-ethylestra-1,3,5(10)-triene-3,17β-diol, is a synthetic estrogen which was never marketed. It occurs as an active metabolite of the anabolic steroids norethandrolone and ethylestrenol formed via aromatase and is believed to be responsible for the estrogenic effects of norethandrolone and ethylestrenol.^[1] The 3-methyl ether of ethylestradiol has been used as an intermediate in the synthesis of certain 19-nortestosterone anabolic steroids,^[2][3] Norethandrolone in particular.^[4]

Other names17α-Ethylestradiol; 17α-Ethylestra-1,3,5(10)-triene-3,17β-diol

Drug classEstrogen

CAS Number

• 2553-34-6 ^Y

PubChem CID

• 66428

Quick facts Clinical data, Other names ...

Ethylestradiol

Clinical data
Other names	17α-Ethylestradiol; 17α-Ethylestra-1,3,5(10)-triene-3,17β-diol
Drug class	Estrogen
Identifiers
IUPAC name (8R,9S,13S,14S,17S)-17-Ethyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
CAS Number	2553-34-6 Y
PubChem CID	66428
ChemSpider	59801
UNII	JL3XDL8DYL
ChEMBL	ChEMBL1627625
CompTox Dashboard (EPA)	DTXSID10948429
Chemical and physical data
Formula	C20H28O2
Molar mass	300.442 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=C3C=CC(=C4)O)C)O
InChI InChI=1S/C20H28O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h5,7,12,16-18,21-22H,3-4,6,8-11H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1 Key:GQHYKMYMSVJXJM-SLHNCBLASA-N

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