Evodiamine

Evodiamine is a chemical compound extracted from the plant genus Tetradium, which has been shown to reduce fat uptake in mouse studies. It is suspected that its mechanism of action is similar to that of capsaicin.^[1] As such, it has been included in some dietary supplements. Neither its fat-burning effects in humans nor any potential side effects have been empirically established.

ATC code

• none

CAS Number

• 518-17-2 ^Y

PubChem CID

• 442088

ChemSpider

• 133343 ^Y

Quick facts Clinical data, ATC code ...

Evodiamine

Clinical data
ATC code	none
Identifiers
IUPAC name 21-Methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one
CAS Number	518-17-2 Y
PubChem CID	442088
ChemSpider	133343 Y
UNII	C01825BVNL
ChEMBL	ChEMBL486598 N
CompTox Dashboard (EPA)	DTXSID10966123
ECHA InfoCard	100.164.846
Chemical and physical data
Formula	C19H17N3O
Molar mass	303.365 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C4N3CCc2c([nH]c1ccccc12)C3N(c5ccccc45)C
InChI InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3 Y Key:TXDUTHBFYKGSAH-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

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Evodiamine acts primarily as a thermogenic and stimulant.^[2]

Evodiamine may also act by increasing the number of serotonin transporters available in the brain, enhancing the reuptake of serotonin.^[3]