Exonuclease 5

EXO5
Identifiers
Aliases	EXO5, C1orf176, DEM1, Exo V, hExo5, exonuclease 5
External IDs	MGI: 1920422; HomoloGene: 41497; GeneCards: EXO5; OMA:EXO5 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	40,516,038 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	120,782,214 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; buccal mucosa cell; ; tendon of biceps brachii; ; testicle; ; granulocyte; ; ganglionic eminence; ; stromal cell of endometrium; ; ventricular zone; ; islet of Langerhans; ; monocyte;
	Top expressed in
	hand; ; medial ganglionic eminence; ; superior cervical ganglion; ; secondary oocyte; ; renal corpuscle; ; medullary collecting duct; ; trigeminal ganglion; ; primary oocyte; ; otolith organ; ; zygote;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; 4 iron, 4 sulfur cluster binding; nuclease activity; iron-sulfur cluster binding; single-stranded DNA 5'-3' exodeoxyribonuclease activity; exonuclease activity; protein homodimerization activity; hydrolase activity; single-stranded DNA 3'-5' exodeoxyribonuclease activity; metal ion binding;
Cellular component	cytosol; nucleus; nucleoplasm; cytoplasm;
Biological process	interstrand cross-link repair; DNA repair; cellular response to DNA damage stimulus; nucleic acid phosphodiester bond hydrolysis;
	Sources:Amigo / QuickGO
Orthologs
	64789
	73172
	ENSG00000164002
	ENSMUSG00000028629
	Q9H790
	Q9CXP9
NM_001346946; NM_001346947; NM_001346948; NM_001346949; NM_001346950;
	NM_001346951; NM_001346952; NM_001346953; NM_001346954; NM_001346955; NM_001346956; NM_022774
	NM_001160043; NM_028457
NP_001333875; NP_001333876; NP_001333877; NP_001333878; NP_001333879;
	NP_001333880; NP_001333881; NP_001333882; NP_001333883; NP_001333884; NP_001333885; NP_073611
	NP_001153515; NP_082733
	Wikidata
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