FOXA3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Hepatocyte nuclear factor 3-gamma (HNF-3G), also known as forkhead box protein A3 (FOXA3) or transcription factor 3G (TCF-3G) is a protein that in humans is encoded by the FOXA3 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesFOXA3, FKHH3, HNF3G, TCF3G, forkhead box A3
Quick facts Available structures, PDB ...
FOXA3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFOXA3, FKHH3, HNF3G, TCF3G, forkhead box A3
External IDsOMIM: 602295; MGI: 1347477; HomoloGene: 3308; GeneCards: FOXA3; OMA:FOXA3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004497

NM_008260

RefSeq (protein)

NP_004488

NP_032286

Location (UCSC)Chr 19: 45.86 – 45.87 MbChr 7: 18.75 – 18.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

HNF-3G is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.[5]

References

Further reading

Related Articles

Wikiwand AI