FUBIMINA

FUBIMINA (also known as BIM-2201, BZ-2201 and FTHJ) is a synthetic cannabinoid that is the benzimidazole analog of AM-2201^[1] and has been used as an active ingredient in synthetic cannabis products.^[2] It was first identified in Japan in 2013, alongside MEPIRAPIM.^[3]

Legal status

• CA: Schedule II
• DE: NpSG (Industrial and scientific use only)
• UK: Class B

CAS Number

• 1984789-90-3 ^Y

PubChem CID

• 124519316

ChemSpider

• 30646758

Quick facts Legal status, Identifiers ...

FUBIMINA

Legal status
Legal status	CA: Schedule II DE: NpSG (Industrial and scientific use only) UK: Class B
Identifiers
IUPAC name (1-(5-fluoropentyl)-1H-benzo[d]imidazol-2-yl)(naphthalen-1-yl)methanone
CAS Number	1984789-90-3 Y
PubChem CID	124519316
ChemSpider	30646758
UNII	U96GD9R3UZ
Chemical and physical data
Formula	C23H21FN2O
Molar mass	360.432 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(C1=NC2=C(C=CC=C2)N1CCCCCF)C3=CC=CC4=CC=CC=C43
InChI InChI=1S/C23H21FN2O/c24-15-6-1-7-16-26-21-14-5-4-13-20(21)25-23(26)22(27)19-12-8-10-17-9-2-3-11-18(17)19/h2-5,8-14H,1,6-7,15-16H2 Key:KUESSZMROAFKQJ-UHFFFAOYSA-N

Close

FUBIMINA acts as a reasonably potent agonist for the CB₂ receptor (K_i = 23.45 nM), with 12x selectivity over CB₁ (K_i = 296.1 nM), and does not fully substitute for Δ⁹-THC in rat discrimination studies.^[4]

Related benzimidazole derivatives have been reported to be highly selective agonists for the CB₂ receptor.^[5]