Famiraprinium
Selective GABAA receptor antagonist
From Wikipedia, the free encyclopedia
Famiraprinium (also known as SR-95103) is a GABAA receptor antagonist used in scientific research.[1]
| Names | |
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| IUPAC name
4-(6-Imino-5-methyl-3-phenylpyridazin-1-yl)butanoic acid | |
| Other names
SR-95103 | |
| Identifiers | |
3D model (JSmol) |
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| ChEMBL | |
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PubChem CID |
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| UNII | |
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| Properties | |
| C15H17N3O2 | |
| Molar mass | 271.320 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It antagonizes certain GABAA receptors with an inhibition constant of 2.2 μM.[2]
Effects
Like other GABA antagonists, it triggers epilepsy-like symptoms. These effects can be antagonized by GABAA agonists like muscimol, proving it is an antagonist.[3]
