Fibrin monomer
Macromolecular complex found in Homo sapiens
From Wikipedia, the free encyclopedia
Fibrin monomers are monomers of fibrin which are formed by the cleavage of fibrinogen by thrombin.[1] Levels of fibrin monomers can be measured using blood tests and can serve as a marker of in vivo fibrinogenesis and coagulation activation.[1][2][3] They may be useful in the evaluation of hypercoagulability,[1] as reflected in research studies done using fibrin monomers.
Levels of fibrin monomers may be increased with pregnancy[1] and by estrogen-containing combined birth control pills.[2]
Research
Significance in venous thromboembolism
Increased amount of soluble fibrin monomers in the blood along with serum D-dimers have been found to be indicators of venous thromboembolism (VTE).[4][5] Detection of VTE in such a way have implications for treating VTE taking place during pregnancy and after hepatobiliary-pancreatic surgery.[4][5]