Flindokalner

Flindokalner (BMS-204352, MaxiPost) is a drug which acts as an opener of BK_Ca large-conductance, calcium-activated potassium channels. It was unsuccessful in clinical trials as a potential treatment for stroke, but continues to be researched for other applications such as Fragile X syndrome.^{[1][2][3][4][5][6][7][8][9]}

Other namesBMS-204352; BMS204352; MaxiPost

ATC code

• None

CAS Number

• 187523-35-9

PubChem CID

• 214350

Quick facts Clinical data, Other names ...

Flindokalner

Clinical data
Other names	BMS-204352; BMS204352; MaxiPost
ATC code	None
Identifiers
IUPAC name (3S)-3-(5-chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)-1H-indol-2-one
CAS Number	187523-35-9
PubChem CID	214350
IUPHAR/BPS	2307
DrugBank	DB16908
ChemSpider	185838
UNII	J57O328W4W
KEGG	D04192
ChEBI	CHEBI:34548
ChEMBL	ChEMBL266510
CompTox Dashboard (EPA)	DTXSID70870176
ECHA InfoCard	100.438.134
Chemical and physical data
Formula	C16H10ClF4NO2
Molar mass	359.70 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=C(C=C(C=C1)Cl)[C@]2(C3=C(C=C(C=C3)C(F)(F)F)NC2=O)F
InChI InChI=1S/C16H10ClF4NO2/c1-24-13-5-3-9(17)7-11(13)15(18)10-4-2-8(16(19,20)21)6-12(10)22-14(15)23/h2-7H,1H3,(H,22,23)/t15-/m0/s1 Key:ULYONBAOIMCNEH-HNNXBMFYSA-N

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