Flutrimazole

Chemical compound From Wikipedia, the free encyclopedia

Flutrimazole is a wide-spectrum antifungal drug. It is used for the topical treatment of superficial mycoses of the skin. Flutrimazole is an imidazole derivative. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole.[1]

ATC code
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Flutrimazole
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (RS)-1-[(2-Fluorophenyl)(4-fluorophenyl)benzyl]-1H-imidazole
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.170.770 Edit this at Wikidata
Chemical and physical data
FormulaC22H16F2N2
Molar mass346.381 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • Fc1ccc(cc1)C(c2c(F)cccc2)(c3ccccc3)n4ccnc4
  • InChI=1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H checkY
  • Key:QHMWCHQXCUNUAK-UHFFFAOYSA-N checkY
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Mechanism of action

It interferes with the synthesis of ergosterol by inhibiting the activity of the enzyme lanosterol 14 α-demethylase.[citation needed]

See also

References

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