Folliculosebaceous cystic hamartoma
Medical condition
From Wikipedia, the free encyclopedia
Folliculosebaceous cystic hamartoma abbreviated as (FSCH) is a rare cutaneous hamartoma consisting of dilated folliculosebaceous units invested in mesenchymal elements.[1]: 676 it typically affects adults, have a predilection for the central face or scalp, with less than 1.5 cm dimension.[2] Clinically, the lesions are asymptomatic, rubbery to firm in consistency, and usually occur on or above the neck in (> 90%) of cases, Histopathologically, FSCH shares several similar features to sebaceous trichofolliculoma, but it is usually possible to differentiate these two tumors.[3]
| Folliculosebaceous cystic hamartoma | |
|---|---|
| |
| Adnexoblastic (folliculosebaceous) trichoid hamartoma | |
| Specialty | Dermatology |
Signs and symptoms
Folliculosebaceous cystic hamartomas frequently manifests as a flesh-colored papule or nodule that is asymptomatic. Folliculosebaceous cystic hamartomas are usually found on the scalp or central face.[4] The lesions are usually 0.5–1.5 cm flesh-colored, exophytic, solitary, rubbery or firm, and partially umbilicated.[5]
Diagnosis
The typical histopathologic features of folliculosebaceous cystic hamartoma lesions are mesenchymal, follicular, and sebaceous elements; these lesions frequently manifest as sebaceous structures that emerge from a core infundibular cyst that is contained inside the dermis.[6] Mesenchymal alterations are frequently observed throughout the stroma and are characterized by fibrillary bundles of collagen with proliferating adipocytes, as well as a rise in capillaries and tiny venules.[7][6] There are clefts separating the neighboring dermis from the epithelial component.[6] In the stroma of lesions, immature adipocytes with lipid droplets and spindle- or starry-shaped nuclei have been observed; these cells are frequently located close to the sebaceous formations.[7]