FOSL2
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene.[5]
External IDsOMIM: 601575; MGI: 102858; HomoloGene: 3845; GeneCards: FOSL2; OMA:FOSL2 - orthologs
Function
The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.[5]