Fungal mating pheromone receptors
Family of G-protein-coupled receptors
From Wikipedia, the free encyclopedia
Fungal pheromone mating factor receptors form a distinct family of G-protein-coupled receptors.
| Fungal pheromone mating factor STE2 GPCR | |||||||
|---|---|---|---|---|---|---|---|
Structure of a Peptide Segment of the 6th Transmembrane Domain of the Saccharomyces cerevisiae alpha-Factor Receptor.[1] | |||||||
| Identifiers | |||||||
| Symbol | STE2 | ||||||
| Pfam | PF02116 | ||||||
| InterPro | IPR000366 | ||||||
| SCOP2 | 1pjd / SCOPe / SUPFAM | ||||||
| OPM superfamily | 6 | ||||||
| OPM protein | 2k9p | ||||||
| CDD | cd14939 | ||||||
| |||||||
Function
Mating factor receptors STE2 and STE3 are integral membrane proteins that may be involved in the response to mating factors on the cell membrane.[2][3][4] The amino acid sequences of both receptors contain high proportions of hydrophobic residues grouped into 7 domains, in a manner reminiscent of the rhodopsins and other receptors believed to interact with G-proteins.
