G-3 (drug)

Pharmaceutical compound From Wikipedia, the free encyclopedia

G-3, also known as 3,4-trimethylene-2,5-dimethoxyamphetamine, is a psychedelic drug of the phenethylamine, amphetamine, and DOx families.[1][2][3] It is one of several homologues of Ganesha (G).[1][2][3]

Other namesG3; Ganesha-3; GANESHA-3; 3C-G-3; 3,4-Trimethylene-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-3,4-(trimethylene)amphetamine; DOG-3
ATC code
  • None
Quick facts Clinical data, Other names ...
G-3
Clinical data
Other namesG3; Ganesha-3; GANESHA-3; 3C-G-3; 3,4-Trimethylene-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-3,4-(trimethylene)amphetamine; DOG-3
Routes of
administration
Oral[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action8–12 hours[1]
Identifiers
  • 1-(4,7-dimethoxy-2,3-dihydro-1H-inden-5-yl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC14H21NO2
Molar mass235.327 g·mol−1
3D model (JSmol)
  • CC(CC1=CC(=C2CCCC2=C1OC)OC)N
  • InChI=1S/C14H21NO2/c1-9(15)7-10-8-13(16-2)11-5-4-6-12(11)14(10)17-3/h8-9H,4-7,15H2,1-3H3
  • Key:GLFZOKOHBIKEKN-UHFFFAOYSA-N
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Use and effects

In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists G-3's dose as 12 to 18 mg orally and its duration as 8 to 12 hours.[1][2][3] The effects of G-3 were reported to include closed-eye imagery, no visuals, fantasy, warmth, mellowness, no body disturbance to hints of body discomfort, and "some suggestions of neurological sensitivity".[1] Music was described as not that exciting and it was felt that there could be easy eroticism but there was no push for it.[1] The drug was rated a "plus-three" on the Shulgin Rating Scale despite there "not [being] much of anything" in one report.[1]

Interactions

Chemistry

Synthesis

The chemical synthesis of G-3 has been described.[1]

History

G-3 was first described in the literature by Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) in 1991.[1]

Society and culture

G-3 is a controlled substance in Canada under phenethylamine blanket-ban language.[4]

See also

References

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