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GAS2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Growth arrest-specific protein 2 is a protein that in humans is encoded by the GAS2 gene.[5][6]

AliasesGAS2, growth arrest specific 2, GAS-2
External IDsOMIM: 602835; MGI: 95657; GeneCards: GAS2
PDBOrtholog search: PDBe RCSB
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GAS2
Identifiers
AliasesGAS2, growth arrest specific 2, GAS-2
External IDsOMIM: 602835; MGI: 95657; GeneCards: GAS2
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_008087
NM_001330607
NM_001330608

RefSeq (protein)

NP_001137302
NP_005247
NP_808221
NP_001338153

NP_001317536
NP_001317537
NP_032113

Location (UCSC)Chr 11: 22.63 – 22.81 MbChr 7: 51.51 – 51.64 Mb
PubMed search[3][4]
Wikidata
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The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.[6]

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