GEM (gene)

Protein-coding gene in humans From Wikipedia, the free encyclopedia

GTP-binding protein GEM is a protein that in humans is encoded by the GEM gene.[5][6][7]

AliasesGEM, KIR, GTP binding protein overexpressed in skeletal muscle
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GEM
Identifiers
AliasesGEM, KIR, GTP binding protein overexpressed in skeletal muscle
External IDsOMIM: 600164; MGI: 99844; HomoloGene: 38024; GeneCards: GEM; OMA:GEM - orthologs
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_181702
NM_005261

NM_010276

RefSeq (protein)

NP_005252
NP_859053

NP_034406

Location (UCSC)Chr 8: 94.25 – 94.26 MbChr 4: 11.7 – 11.71 Mb
PubMed search[3][4]
Wikidata
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The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.[7]

References

Further reading

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