GJC1

GJC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3SHW
Identifiers
Aliases	GJC1, CX45, GJA7, gap junction protein gamma 1
External IDs	OMIM: 608655; MGI: 95718; HomoloGene: 4016; GeneCards: GJC1; OMA:GJC1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	44,830,816 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	102,710,526 bp
RNA expression pattern
	Top expressed in
	tail of epididymis; ; seminal vesicula; ; cartilage tissue; ; secondary oocyte; ; visceral pleura; ; saphenous vein; ; placenta; ; ventricular zone; ; epithelium of colon; ; myometrium;
	Top expressed in
	abdominal wall; ; renal corpuscle; ; internal carotid artery; ; superior surface of tongue; ; vas deferens; ; endocardial cushion; ; tail of embryo; ; external carotid artery; ; medullary collecting duct; ; primitive streak;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ion channel activity; gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling; gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling; gap junction channel activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; intercalated disc; plasma membrane; cell junction; gap junction; connexin complex;
Biological process	muscle contraction; cell development; cardiac muscle tissue development; cell-cell signaling; vasculogenesis; cell communication; development of the heart; ion transmembrane transport; atrial cardiac muscle cell action potential; cell-cell junction assembly; visual perception; chemical synaptic transmission; gap junction assembly; SA node cell to atrial cardiac muscle cell communication by electrical coupling; AV node cell to bundle of His cell communication by electrical coupling; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	10052
	14615
	ENSG00000182963
	ENSMUSG00000034520
	P36383
	P28229
	NM_001080383; NM_005497
	NM_001159382; NM_001159383; NM_008122; NM_001359040
	NP_001073852; NP_005488
	NP_001152854; NP_001152855; NP_032148; NP_001345969
	Wikidata
View/Edit Human	View/Edit Mouse

Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) and connexin 45 (Cx45) — is a protein that in humans is encoded by the GJC1 gene.^[5]^[6]